Non-Invasive Method for Monitoring Real-Time Oxygen Concentrations during Hematopoietic Stem/Progenitor Cell (HSPC) Culture

The SDR SensorDish® Reader has allowed for the quantitation of in vitro oxygen concentrations during the culture of hematopoietic stem/progenitor cells isolated from human umbilical cord blood. The influence of simulated physiological oxygen concentrations on HSPC proliferation, cell cycle status and expression of markers of stem cell phenotype or differentiated cell types were examined concurrently with the monitoring of real-time oxygen concentrations in the cell culture media. Timothy McKinnon, Postdoctoral Fellow at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, demonstrated the usefulness of this system for examinations of cell phenotype and function in conditions that effectively mimic the in vivo oxygen environment.

Child-Resistant Packaging

Accidental poisoning is common amongst young children. As a natural part of their early development children explore their environment using their senses to ‘play’ with items that are new to them. They cannot differentiate between items that are safe and items that may be harmful to them. Tim Bollans, Marketing & Sales Executive at Burgopak Healthcare & Technology, examines how child-resistant packaging has been a part of the pharmaceutical and healthcare industries for the last forty-five years, but only recently has the need for real innovation been at the forefront of the industry

Robots Set for a Fruitful Future in Pharmaceutical Processes

The food and beverage and pharmaceutical industries have often mirrored each other in the way they use similar technologies in their respective production processes. Automation is one such area, particularly when it comes to robotics. Having been embraced in increasing numbers by food manufacturers, robots are increasingly finding their way into many pharmaceutical manufacturing processes as well. Nigel Platt, Sales & Marketing Manager for ABB’s UK robotics business, explains the benefits robots have already been proven to deliver in pharmaceutical applications, and examines the scope for future application of the technology.

What is Cleaning in Place? How Does it Work, and Where Should You Use It?….A Basic Primer Answers These & Many More Questions

Cleaning in Place has been around for approximately 50 years, and is commonly used in hygiene critical industries, such as food, beverage and pharmaceuticals, to clean a wide range of plants. Timo Bleschke, Product Manager Pneumatic and Process Interfaces at Bürkert Fluid, explores Cleaning in Place within the pharmaceutical industry.

The Role of the Medical Photographer within Clinical Research

Clinical research organisations are becoming more aware of the benefits of engaging with medical photographers, who are highly specialised in their profession, to ensure the accuracy, suitability and integrity of the visual data that supports or validates a clinical trial. Jo Truelove, Senior Medical Photographer at Illingworth Research, explains what was once seen as an optional extra is now being viewed as a service that has a substantial impact on proving or disproving a compound’s value in a study, potentially saving significant costs and, more importantly, lives

Amsterdam BioMet: Building the Metropolitan Area for Life Sciences

At the heart of European Life Sciences, the Netherlands offers a longstanding tradition of biomedical research. In the Amsterdam Metropolitan Area, scientific excellence is empowered by metropolitan strengths, turning the region into a unique hotspot for life sciences. Sandra Migchielsen, Senior Project Manager / Cluster Manager for Life Sciences at Amsterdam Innovation Motor, hosting BIO-Europe Spring® in March 2012, illustrates how the region is building its niche as the Netherlands’ only BioMetropolitan Area.

Molecules to Markets

In any major pharmaceutical operation there are hundreds of different functions, departments and teams. Trying to understand how it all fits together can be a nightmare. Just to make it more complicated there are also different ‘views’ of the organisation – functional hierarchy, therapy areas, project structures, and so on. John Faulkes, Key Associate from PPMLD describes how the pharma business fits together.